Dolphins running game vs. Bills run defense
RB Reggie Bush (895 yards, 4.5 yards per carry) faces the NFL's 30th-ranked run defense in yards per game (144.1). He's also coming off a 104-yard performance against Jacksonville. Miami is missing Daniel Thomas (knee), its pass blocking/short-yardage/red zone specialist. But his loss shouldn't affect Bush, who is on the verge of back-to-back 1,000-yard seasons. LB Nick Barnett (97 tackles) and DT Kyle Williams will be the biggest impediments to success for the Dolphins. EDGE: Dolphins
Dolphins passing game vs. Bills pass defense
QB Ryan Tannehill
has gone three games without an interception and has completed 60.3
percent of his passes in his last four games. The health of WRs Davone Bess (back) and Brian Hartline (back) is a huge factor, however. Buffalo, the league's 15th-ranked pass defense, was tough on Tannehill last time. S Jairus Byrd and LB Bryan Scott had INTs in the final two minutes. If the WRs aren't healthy this could get ugly. EDGE: Bills
Bills running game vs. Dolphins run defense
RB C.J. Spiller
(1,047 yards, 6.5 ypc) had 91 yards rushing the last time these teams
played. Look for him to do something along those lines again. Miami's
run defense is eighth (100.9 yards per game) and tackles Randy Starks, who is questionable, and Paul Soliai make things tough. LB Karlos Dansby (111 tackles) also does good work. But Spiller is so shifty he only needs a small crack. Look for S Reshad Jones to crowd the line of scrimmage often. EDGE: Bills
Bills passing game vs. Dolphins pass defense
Miami's banged-up secondary is the biggest factor. CB Nolan Carroll (knee) is ailing and S Jimmy Wilson (hip) is slowed. And the Dolphins are the 26th-ranked pass defense with him on the field. QB Ryan Fitzpatrick (22 TDs, 19 INTs) is ranked 19th with an 83.5 passer rating and WR Stevie Johnson (891 yards, 6 TDs) has been effective. Fitzpatrick has 5 TDs and 5 INTs in his last five games. Still, it's tough to overcome missing/slowed personnel. EDGE: Bills
Dolphins special teams vs. Bills special teams
Miami signed K Nate Kaeding and placed Dan Carpenter (groin) on injured reserve. KOR/PR Marcus Thigpen had a 96-yard KOR TD when these teams played. Of course, that was after Bills' PR Leodis McKelvin had a 79-yard TD. But McKelvin, the NFL in punt return average at 18.7 yards, is on injured reserve (groin) and won't play. Thigpen is third in kickoff return average (28.7) and tied for fifth in punt return average (12.0). Bills K Rian Lindell (20-for-21 on FGs) has made 95.2 percent of his attempts. Miami P Brandon Fields (50.6 yards per punt gross average) is a master at flipping field position. EDGE: Dolphins
Intangibles
Buffalo's defense is tied for last in points allowed (28.7 per game). That's not good for a road team. But Miami is without RB Daniel Thomas (knee) and TE/FB Charles Clay (knee) and the WRs will be affected by injury, too. Look for Dolphins offensive coordinator Mike Sherman to continue using multiple sets and formations, and allow QB Ryan Tannehill to roll out and use his feet. Being at home should be a great asset in a game between fairly evenly-matched teams. EDGE: Dolphins
Prediction: Bills 20, Dolphins 17.
RB Reggie Bush (895 yards, 4.5 yards per carry) faces the NFL's 30th-ranked run defense in yards per game (144.1). He's also coming off a 104-yard performance against Jacksonville. Miami is missing Daniel Thomas (knee), its pass blocking/short-yardage/red zone specialist. But his loss shouldn't affect Bush, who is on the verge of back-to-back 1,000-yard seasons. LB Nick Barnett (97 tackles) and DT Kyle Williams will be the biggest impediments to success for the Dolphins. EDGE: Dolphins
Dolphins passing game vs. Bills pass defense
Bills running game vs. Dolphins run defense
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Bills passing game vs. Dolphins pass defense
Miami's banged-up secondary is the biggest factor. CB Nolan Carroll (knee) is ailing and S Jimmy Wilson (hip) is slowed. And the Dolphins are the 26th-ranked pass defense with him on the field. QB Ryan Fitzpatrick (22 TDs, 19 INTs) is ranked 19th with an 83.5 passer rating and WR Stevie Johnson (891 yards, 6 TDs) has been effective. Fitzpatrick has 5 TDs and 5 INTs in his last five games. Still, it's tough to overcome missing/slowed personnel. EDGE: Bills
Dolphins special teams vs. Bills special teams
Miami signed K Nate Kaeding and placed Dan Carpenter (groin) on injured reserve. KOR/PR Marcus Thigpen had a 96-yard KOR TD when these teams played. Of course, that was after Bills' PR Leodis McKelvin had a 79-yard TD. But McKelvin, the NFL in punt return average at 18.7 yards, is on injured reserve (groin) and won't play. Thigpen is third in kickoff return average (28.7) and tied for fifth in punt return average (12.0). Bills K Rian Lindell (20-for-21 on FGs) has made 95.2 percent of his attempts. Miami P Brandon Fields (50.6 yards per punt gross average) is a master at flipping field position. EDGE: Dolphins
Intangibles
Buffalo's defense is tied for last in points allowed (28.7 per game). That's not good for a road team. But Miami is without RB Daniel Thomas (knee) and TE/FB Charles Clay (knee) and the WRs will be affected by injury, too. Look for Dolphins offensive coordinator Mike Sherman to continue using multiple sets and formations, and allow QB Ryan Tannehill to roll out and use his feet. Being at home should be a great asset in a game between fairly evenly-matched teams. EDGE: Dolphins
Prediction: Bills 20, Dolphins 17.